PlaqueOff™ for Animals

VOHC accepted, ProDen PlaqueOff Animal does not rely on topical application or friction. The product is ingested and works systemically.

The natural compound in the product comes out through the saliva and works to break down the bacterial biofilm that forms on the teeth and gums. This is how the natural bacteria in the mouth take hold onto the teeth and gums, colonizing and creating the oral problems of plaque and tartar, bad breathe and gingivitis. It does not change the pH of the mouth or kill off the normal levels of bacteria.

ProDen PlaqueOff has been proven to reduce plaque and tartar on the teeth and gums, depending on composition, diet and how long it has been there. It then works to prevent bad breath, plaque and tartar from returning.

Patients generally begin to see results over a 2-8 week period, and will see further benefits with continued use.

We love it!

PlaqueOff has done wonders for my older dog’s teeth. They stopped bleeding and his breath is better.

I cannot believe how wonderful this product is. I saw results on my dog in 4 weeks – the tartar had receded by almost 50% and in just over two months, everything was gone! I would say this is the best product for plaque and tartar removal that I have ever used on my dogs!!

Fantastic stuff. My two Springers now have ‘pearly white’ teeth. To have the Vet de-scaling the dogs would have cost £150 each for it merely to have returned again and again.

Brilliant product have been using for years (recommended to me by a friend) and my two elderly dogs have perfect teeth with no plaque at all!

We have previously relied on the tooth scaler to get the teeth clean, now we’ve found a better alternative – PlaqueOff Animal Powder!

Our vet was (tongue in cheek) ‘unhappy’ with us having Dexter on PlaqueOff…. He stated that since we have had Dexter on this his teeth are in, and I quote, “perfect condition”……

So, yes, undeniably, PlaqueOff – the results speak for themselves.

Dental care is unfortunately one of the most overlooked health issues that pet owners concern themselves with.

As in humans, plaque bacteria constantly forms in the mouth of all cats and dogs. Once plaque has calcified into tartar it can no longer be brushed off. In many cases it has to be removed by a vet using ultrasound and anaesthetic.

If tartar build-up is left untreated it can result in bad breath, gum disease, tooth decay and premature tooth loss.

Tartar that is allowed to remain for too long can also cause infections that can spread throughout the body and damage the heart, lung, liver and negatively affect kidney functions.

ProDen PlaqueOff Powder provides an easy complement to your pet’s regular oral hygiene care.The active ingredient is a specially selected alga, Ascophyllum nodosum, harvested along the North Atlantic coast.

The 100% all natural product, ProDen PlaqueOff® Powder is free from additives and artificial preservatives and contains no gluten or added sugar.


Registration Number: V22114

Untreated tartar can cause damage to the foundation of the tooth and result in loosening of the tooth, known as periodontitis.

As the gums swell owing to inflammation, the tooth pocket deepens. Bacteria coatings spread out down into the tooth pocket and the connective tissue in the bottom of the pocket dissolves.

Consequently, the tooth pocket deepens further and the coating of bacteria can grow down into the root. The coating mineralises into tartar and the inflammation process accelerates.

The root membrane threads now begin to deteriorate owning to the inflammation and the jaw bone erodes. The continued deepening of the tooth pocket keeps pace with the growth of plaque and dissolving of the root membrane and jawbone.

Finally, the tooth loosens.

Periodontitis is a late symptom of the disease.

Signs of acute periodontitis can include teeth moving about or becoming loose.

Spontaneous bleeding of the gums, formation of pus, boils, fistulas and bad breath are other signs.

Periodontitis can be defined as a chronic disease that establishes itself insidiously. It can be present for a long period of time without producing any noticeable symptoms.

Tartar, swollen and bleeding gums, broken teeth and other states of ill-health in the gums frequently give rise to diarrhoea in cats/dogs and humans.

The bacteria that thrive in the gingival pockets and attack the teeth, most especially the roots, travel down into the digestive tracts.

Cats with broken teeth often suffer from toothache. They dribble and their condition deteriorates and they lose weight because they can no longer eat enough.

Bad dental status frequently paves the way for secondary infections.

In serious cases, an infected tooth can cause blood-poisoning, which in turn can cause pericarditis (inflammation of the pericardium, the membranous sac that encloses the heart).  Unless treated, this condition can lead to death

Bacteria loves tartar!

Toxics from the bacteria irritate the tissue and the bone retracts.

The gingival pocket (tooth pocket) gradually deepens and the
vicious circle commences. Now there is room for more tartar  Oral Health Deteriorationand more bacteria. In the final stage, when almost all the bone has retracted, the teeth loosen and the infection is now so acute that swelling and pain become the norm. The body soon senses the untreated tooth in a deep pocket as being a foreign object.

Eventually the tooth is pushed up and loosens.

Bad breath often reveals that a dog or cat has tartar and perhaps such acute loosening of the teeth that several of these cannot be saved. Wild cats also suffer from tartar, even if they live a more “natural” life.


Plaque is the sticky, thin layer of bacteria and food remnants that builds up continuously in the mouth.  If the first soft coating is allowed to remain in place, this will eventually calcify and harden into tartar.


Tartar forms as a yellow-brown coating at the base of teeth along the top of the gums.

The composition in saliva affects the formation of tartar, which in some cases can be genetic.

Tartar builds up above the rim of the gums as minerals contained in saliva spread out across the teeth.

Beneath the gum rim the tartar looks darker owing to colouring from minor bleeding in the gums.

Clinical Trials

How does it work?

Dental plaque is made up of a community of microbes that have organised themselves into a complex and tenacious film – a biofilm.

Unlike other methods of plaque control, ProDen PlaqueOff™ Animal works systemically, and is thought to disrupt the biofilm, reducing levels of plaque and calculus as well as improving breath odour.

Recent research shows that this especially selected seaweed (SW1313 / D1070) has a positive effect on plaque and calculus reduction over time.

PlaqueOff Clinical Trials

PlaqueOff Clinical Trials

Clinical Pilot Studies

Oral effects of ProDen PlaqueOff Animal

After testing our product on humans, we asked a professional research team in the USA to perform a study on dogs. The aim of the study was to investigate the effect of ProDen PlaqueOff® on dental plaque, bleeding, oral malodor, saliva pH, urine pH and blood composition.

You can download PDF files of the studies here:

PlaqueOff® Animal study: Dogs & Cats

This study was performed by Annalena Sörensson, Varbergsveterinärerna (Varberg Veterinary Clinic), during 2007-2008. In total, 9 dogs and 1 cat completed the study. Results were seen as early as after 2 months.

You can download the PDF file here:

Oral Care